Engineering

Tris Pharma

Sr. Metrologist

**Tris Pharma, Inc. (www.trispharma.com) is a leading privately-owned US biopharmaceutical company** focused on development and commercialization of innovative medicines in ADHD, spectrum disorders, anxiety, pain and addiction addressing unmet patient needs. We have \>150 US and International patents and market several branded ADHD products in the US. We also license our products in the US and ex-US markets. Our robust pipeline of innovative products employing our proprietary science and technology spans neuroscience and other therapeutic categories.

**Our science and technology make us unique, but our team members set us apart**; they’re the engine fueling Tris’ passion and innovation. Our colleagues understand the criticality of operating a successful business and take pride in the company’s success. Equally important is how we interact on a daily basis. We believe in each other and in respectful, open and honest communication to help support individual and team success.

**We have an immediate opening in our Metrology department in Monmouth Junction, NJ for an experienced Senior Metrologist.**

The Sr. Metrologist supports Analytical laboratories by performing routine calibration and instrument performance verification, maintenance and repairs on highly complicated instrumentation including, but not limited to: High Pressure Liquid Chromatography/Ultra Performance Liquid Chromatography (HPLC/UPLC), Gas Chromatography (GC), ultra-violet visible spectrophotometry (UV-Vis), Fourier Transform Infrared (FTIR), Muffle Furnace, Viscometers, Density Meters, Melting Point, Dissolution and Autosampler, Polarimeter, ICPMS, GCMS, etc. following analytical methods, United States Pharmacopeia (USP)/National Formulary (NF) Chapters, protocols, Standard Operating Procedures (SOPs) under current Good Manufacturing Practices (cGMPs) and company policies.

Collaborating closely with, and under the direct supervision of laboratory management, the incumbent carries out laboratory work to support laboratory activities and performs special projects as assigned. She/he also writes and assists investigation related to instrument calibration failures or other instrument related issues.

ESSENTIAL FUNCTIONS

• Carries out responsibilities in accordance with company policies, SOPs and state, federal and local laws

• Performs routine calibration and instrument performance verification, maintenance, and repairs on highly complicated instrumentation such as HPLC/UPLC, GC, UV-Vis, FTIR, GCMS, ICPMS, Muffle Furnace, Viscometers, Density Meters, Melting Point, Dissolution and Autosampler, Polarimeter etc.

• Processes and reports calibration results using instrument specific data processing software; Documents all activities in legible manner following established formats and good documentation procedures

• Initiates, writes and assists investigation related to instrument calibration failures or another instrument related issues

• Creates, reviews and revises SOPs related to metrology activities

• Initiates change control related to analytical instrument

• Assesses critical analytical instrument/equipment performance

• Executes analytical instrument qualification protocols and drafts qualification reports

• Contacts and obtains technical information from vendors or service providers

• Analyzes samples to evaluate instrumentation performance and troubleshoot instrument malfunction and/or breakdown, etc.

• Trains and mentors lower-level Metrologists and assists them during routine metrology

• Safely and properly dispose of chemical waste, as needed

• Complies with all company policies and procedures, including safety rules and regulations and adheres to cGMPs and current Good Documentation Practices (cGDPs)

Requirements

KNOWLEDGE/SKILLS/ABILITIES REQUIRED

· Bachelors in Chemistry, Engineering or related scientific field and minimum 6 years lab experience in a GMP related industry or minimum 8 years related experience handling analytical equipment in pharmaceutical or biotechnology industry working in Metrology, Method Validation (MV), Quality Control (QC) or related laboratories **REQUIRED**

· Experience working with Food and Drug Administration (FDA), current Good Laboratory Practices (cGLPs), cGMPs, SOPs and regulatory rules, regulations, and guidelines **REQUIRED**

· Hands on experience performing routine metrology, calibration, maintenance and/or troubleshooting of analytical instrumentation (i.e., HPLC/UPLC, GC, Dissolution Apparatus and Autosamplers, UV-Vis, Density Meter, Balances, Ovens, Viscometers, Melting Point apparatus, Refractometer, Polarimeter, Media Dispenser Ezfill, etc.) **REQUIRED**

· Experience performing or assisting in laboratory or metrology investigations **REQUIRED**

· Previous experience creating, reviewing, or revising SOPs **REQUIRED**

· Proficiency with Empower and/or other laboratory software **REQUIRED**

**Work Arrangements:**  This position requires working in our Monmouth Junction, NJ labs five (5) days per week.

**Anticipated salary range:**  $95 to $115k/yr. Base salary offered is contingent on assessment of candidate’s education and experience level relative to requirements of the position and a review of related industry standards and internal equity.

**Additional benefits:**  In addition to base salary, full-time employees are also eligible for incentives, including, but not limited to: bonus eligible, medical, dental, vision, Rx insurance, 401K with match, life insurance, paid Company Holidays, PTO, Paid Volunteer Time and Employee Resource Groups.

Tris Pharma, Inc. offers a highly competitive compensation and benefits package. To build and enhance our diverse workforce, we encourage applications from individuals with disabilities, minorities, veterans, women, LGBTQ, etc. Tris Pharma, Inc. is an Equal Opportunity Employer. #LI-office

New Jersey

AbbVie

Associate Engineer, Technology II

Company Description

**About AbbVie**

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at [www.abbvie.com](<http://www.abbvie.com/>). Follow @abbvie on [LinkedIn,](<https://www.linkedin.com/company/abbvie/>) [Facebook](<https://www.facebook.com/AbbVieGlobal/>), [Instagram](<https://www.instagram.com/abbvie/>), [X](<https://twitter.com/abbvie>) and [YouTube.](<https://www.youtube.com/user/AbbVie>)

Job Description

AbbVie IR Scientific Computing Solutions is seeking a highly motivated Technology Engineer to implement, configure, maintain, and support software and technology solutions across on-premises, cloud, and hybrid high-performance computing (HPC) environments. This role is responsible for enabling computational research and development by integrating scientific applications with HPC resources, automating software deployment, supporting HPC integration with internal platforms, assisting users, resolving technical issues, and maintaining reliable technical documentation. The successful candidate will have strong problem-solving skills, technical precision, and working knowledge of Linux systems, HPC operations, software environments, containers, and CI/CD practices. This individual will help deliver secure, scalable, reliable, and efficient solutions while partnering with R&D stakeholders and contributing to collaboration, innovation, and continuous improvement.

**Responsibilities:**

- Install, configure, maintain, and support academic, open-source, and commercial software applications in HPC environments (e.g., Schrödinger, Posit) using commercial installers, source builds, package managers, and container-based methods.
- Partner with the HPC operations team to configure and integrate HPC applications with workload schedulers and orchestration platforms (e.g., Slurm and Kubernetes).
- Develop and maintain CI/CD pipelines for automating the build and deployment of software images.
- Enable reliable integration with HPC environments and access to computational resources from other internally developed applications.
- Assist users with access to and effective use of HPC environments, software applications, and computational workflows.
- Investigate, troubleshoot, and resolve reported issues, errors, and performance problems affecting HPC users and supported applications.
- Create, maintain, and improve administrator- and user-facing HPC documentation, including installation procedures, configuration standards, usage guidance, and troubleshooting information.
- Analyze and communicate technical issues, deviations, and recommendations to stakeholders; coordinate with infrastructure, application, and research teams to deliver reliable solutions.

Qualifications

- Bachelor’s Degree in Computer Science, Computational Science, Information Technology, or related field with 2 years' experience; OR Master’s Degree with no additional experience.
- Experience running computational software in on-premises or cloud-based HPC environments.
- Familiarity with Linux operating systems and command-line environments.
- Experience with HPC schedulers or orchestration platforms, such as Slurm or Kubernetes.
- Demonstrated ability to troubleshoot software installation, configuration, integration, and runtime issues.
- Experience using software, package, and environment management tools such as conda, mamba, EasyBuild, or Spack.
- Experience containerizing applications and environments using technologies such as Docker or Apptainer.
- Familiarity with environment modules on HPC systems.
- Experience using CI/CD tools to automate workflows (e.g., GitHub Actions)
- Demonstrated strong collaboration, communication, documentation, and problem-solving skills.

Additional Information

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:

- The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this roleat the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on manyfactors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.
- We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.
- This job is eligible to participate in our short-term incentive programs.

Note: No amount of pay is considered to be wages or compensation until such amount isearned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that areallocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolutediscretion, consistent with applicable law.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.

US & Puerto Rico only - to learn more, visit [https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html](<https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html>)

US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:

[https://www.abbvie.com/join-us/reasonable-accommodations.html](<https://www.abbvie.com/join-us/reasonable-accommodations.html>)

Illinois

Amgen

Director Engineering

**Join Amgens Mission of Serving Patients**

At Amgen, if you feel like youre part of something bigger, its because you are. Our shared missionto serve patients living with serious illnessesdrives all that we do.

Since 1980, weve helped pioneer the world of biotech in our fight against the worlds toughest diseases. With our focus on four therapeutic areas Oncology, Inflammation, General Medicine, and Rare Disease we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, youll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, youll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

**Director Engineering**

**What you will do**

Lets do this. Lets change the world. In this role as a member of the AOH Engineering leadership team, the director will provide leadership, strategy, and tactical direction for the engineering and maintenance teams supporting the assembly and packaging lines in AOH 24/7 operation. This position reports directly to the Executive Director F&E and will manage a dynamic team whose responsibilities include engineering and maintenance.

Key responsibilities include:

- Ensure safety of all personnel during plant operations and engineering activities
- Ensure that all staff are adequately trained and comply with all GMP standards and procedures
- Maximize staff productivity and the efficient use of available resources
- Maintain and improve plant capability and equipment reliability in partnership with plant leadership and other technical staff
- Leverage resources to support ongoing department capital project investment
- Identify areas of potential improvement, conduct analyses, recommend solutions, sponsor improvement projects, and implement as required
- Maintain and develop key performance indicators, supervise, assess, and develop staff, and ensure that all targets and milestones are completed on time and on budget
- Interface with a diverse Amgen internal network including AOH clients (plant and area directors and front-line managers), Facilities & Engineering leadership (Engineering and Automation), Engineering Technical Authority, Technology, Global Capital Project Management, Environmental Health and Safety, and Process Development

Specific responsibilities include:

- Oversee a safe and compliant workforce working with a highly utilized commercial operations site
- Provide day-to-day, small project, and plant shut-down support
- Work with a diverse group of clients, technologies, and integrated systems in product development all in a GMP and highly regulated setting
- Manage partners and drive new business processes to ensure continuous and sustained improvements
- Ensure readiness and compliance for internal audits, external agency audits, and partner visits
- Present engineering plans, progress, and status updates to project stakeholders
- Review and approve proposed engineering designs, and equipment improvements and changes
- Perform administrative and oversight functions in approving proposals and expenditures
- Participate in the development of department expenditure requests and partner with the projects teams to define the best engineering solution inclusive of long-term equipment performance
- Deliver effective troubleshooting and timely response to reduce downtime
- Drive robust equipment reliability

**What we expect of you**

We are all different, yet we all use our unique contributions to serve patients. The engineering professional we seek is a leader and a strong strategic problem solver with these qualifications.

**Basic Qualifications:**

Doctorate degree and 4 years of Manufacturing, Packaging or Quality experience in pharmaceutical, medical device or biotechnology companies experience

OR

Masters degree and 8 years of Manufacturing, Packaging or Quality experience in pharmaceutical, medical device or biotechnology companies experience

OR

Bachelors degree and 10 years of Manufacturing, Packaging or Quality experience in pharmaceutical, medical device or biotechnology companies experience

In addition to meeting at least one of the above requirements, you must have at least 4 years experience directly managing people and/or leadership experience leading teams, projects, programs, or directing the allocation or resources. Your managerial experience may run concurrently with the required technical experience referenced above

**Preferred qualifications:**

- Typically, 12+ years of relevant work experience with 8+ years experience in an operations / manufacturing environment
- Typically, 10+ years experience with regulated environments (i.e. FDA/cGMP, OSHA, EPA) preferred
- Must have experience leading an engineering department in a regulated GMP environment
- Knowledge of GMP manufacturing equipment and their design and operational aspects
- Excellent organizational and administrative leadership skills
- Ability to work and influence locally and across Amgens network
- Ability to work in a highly dynamic organization with a demanding environment
- Must have excellent verbal and written communication skills, as well as the ability to actively, and cooperatively work with cross-functional teams
- Demonstrated team motivation, leadership, and mentoring/staff development skills
- Understand regulatory trends in the industry. Direct experience with FDA or equivalent regulatory body
- Ability to manage multiple resource demands and prioritization, assess project effectiveness, and efficiency and manage demand
- Proven ability to motivate staff and establish and communicate visions/missions
- Proven ability to delegate and manage the work of others
- Demonstrate a high degree of creativity, foresight, and mature judgment in anticipating and solving problems by translating data into actionable solutions

**What you can expect of us**

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, well support your journey every step of the way.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:

- A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
- A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
- Stock-based long-term incentives
- Award-winning time-off plans
- Flexible work models, including remote and hybrid work arrangements, where possible

**Apply now**

**for a career that defies imagination**

Objects in your future are closer than they appear. Join us.

**careers.amgen.com**

**Sponsorship**

Sponsorship for this role is not guaranteed.

In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

Ohio

Senior Manager Utilities Engineering

**Join Amgens Mission of Serving Patients**

At Amgen, if you feel likeyourepart of something bigger,itsbecause you are. Our shared missionto serve patients living with serious illnessesdrives all that we do.

Since 1980,wevehelped pioneer the world of biotech in our fight against the worlds toughest diseases. With our focus on four therapeutic areas Oncology, Inflammation, General Medicine, and Rare Disease we reach millions of patients each year. As a member of the Amgen team,youllhelp make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities thatliewithin them,youllthrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Be part of Amgen's newest and most advanced drug substance manufacturing plant. When completed, the AmgenFleXBatch facility will combine the latest in disposable technologies with traditional stainless-steel equipment to allow for maximum flexibility in operations. TheFleXBatch facility will not only feature the best in-class drug substance manufacturing technologies with embedded industry 4.0 capabilities, but it will also integrate sustainability innovations to reduce carbon and waste, as part of Amgen's plan to be a carbon-neutral company by 2027.

**Senior Manager Utilities Engineering**

**What you will do**

Lets do this! Lets change the world! The Senior Manager Utilities Engineering will join the Facilities & Engineering (F&E) group reporting to the Facilities & Engineering (F&E) Director. In this vital role, you will lead the Utilities Engineering teams andwill provide technical leadership to the utilities engineering team while supporting 24/7 operations.

Job responsibilities include:

- **Sitedesign, construction, start-up, and operational readiness:**

- Build a team of Utilities Engineers and serve as the main point of contact for the UtilitiesEngineering function.

- Support the start-up of all site utility systems and transfer of ownership to the F&E utilities team.

- Develop and implement long term strategy for technical support of installed systems and equipment including system setups for CMMS, etc.

- Support the development and implementation of goals and objectives and associated budgets for all utility engineering services including but not limited tomechanical and HVAC systems.

- Ensure utility engineering programs are aligned with cGMP and safety requirements, local/ global regulations, and Amgen Maintenance excellence standards.

- Ensure that procedures are in place for cGMP and daily activities are followed by area personnel and contractors.

- Ensure safety of all personnel during plant construction,start-up operations, and maintenance activities across multiple shifts providing 24/7 plant and utility coverage.

- **Site Operations:**

- Responsible for leading the Amgen NC F&E Utility Engineering staff supporting continuous clean and plant utility operations including electrical and HVAC systems at the site.

- Accountable for system ownership for Building and Process utility systems and for supplier management including:

- GMP utilities such as Plant Utilities, Purified Water (PW), Water for Injection (WFI), Clean Steam, Clean Compressed Air, and Process Gases, as well as non-GMP utilities such as waste management, electrical systems, boiler room operations, chilled water systems, plant steam, industrial gases, HVAC systems, and compressed air systems.

- Manage system ownership by providing adequate resources and technical talent and expertise, maintenance procedures, providing adequate system validation support, monitoring performance data, providing adequate training materials, and ensuring operating procedures are followed.

- Develop and support equipment maintenance programs, ensure the availability of spare parts, andcoordinatingmaintenance activities to ensure systems are in proper working order.

- Ensures site readiness and compliance for internal audits, external agency audits, and partner visits.

- Lead and support continuous improvement initiatives including improvements to safety, reliability, efficiency, and sustainability

- Maintain and improve utility system capability and reliability in partnership with engineering leadership and technical staff.

- Effectively collaborate with key customers and support groups (e.g. Manufacturing, Quality, Environmental Health & Safety, and Engineering).

- Have oversight and lead execution of complex Utilities related initiatives and projects. Provide expertise and resources for capital project execution.

- Establish clear expectations and priorities to staff. Encourage a culture of continuous improvement, partnership, and knowledge sharing. Provide development opportunities, feedback, and actively listen to staff.

- Maintain and develop key performance indicators of maintenance performance, supervise, assess, develop staff and ensure that all targets and milestones are completed on time and on budget.

- Participate in the budgeting process for Utilities, including forecasting costs, managing expenditures, and ensuring efficient allocation of resources.

- Up to 10% domestic/international travel

**What we expect of you**

We are all different, yet we all use our unique contributions to serve patients. The automation professional we seek enjoys challenges and is motivated to help serve patients with these qualifications.

Basic Qualifications:

- Doctorate degree and 2 years of engineering experience

OR

- Masters degree and 6 years of engineering experience

OR

- Bachelors degree and 8 years of engineering experience

OR

- Associates degree and 10 years of engineering experience

Or

- High school diploma / GED and 12 years of engineering experience

And

- 2 years of managerial experience directly managing people and/or leadership experience leading teams, projects, programs or directing the allocation of resources

Preferred Qualifications:

- 6+ years experience in Utilityengineeringwithin the biotechnology and/or pharmaceutical or other regulatory environments.

- 3+ years experience of ensuring compliance in a highly regulated environment

- Demonstrated interpersonal and facilitation skills and ability to work in a collaborative team-based environment

- Ability to lead multiple tasks and effectively set priorities

- Direct knowledge of GMPutilities such as Purified Water (PW), Water for Injection (WFI), Clean Steam, Clean Compressed Air, and Process Gases, as well as non-GMP utilities such as waste management, electrical systems, boiler room operations, chilled water systems, plant steam, industrial gases, HVAC systems, and compressed air systems.

- Strong knowledge of Computerized Maintenance Management Systems.

- Demonstrated skill in analyzing and improving facilities related quality systems

- Ability and willingness to mentor and develop engineering staff and embrace a team-based culture that relies on collaboration for effective decision-making.

- Strong leadership, technical writing, and communication/presentation skills.

- Work schedule flexibility as required to support 24/7 operations, requiring occasional after-hours engineering coverage.

**Thrive**

**What you can expect of us**

As we work to develop treatments that take care of others, we also work to care for our teammates professional and personal growth and well-being.

Amgen offers a Total Rewards Plan comprising health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities including:

- Comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts.

- A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan

- Stock-based long-term incentives

- Award-winning time-off plans and bi-annual company-wide shutdowns

- Flexible work models, including remote work arrangements, where possible

**Apply nowfor a career that defies imagination**

Objects in your future are closer than they appear. Join us.

**careers.amgen.com**

\#AmgenNorthCarolina

Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

We will ensure that individuals with disabilities are provided reasonable accommodation toparticipatein the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

North Carolina

Nurix Therapeutics

Associate Director, Chemical Engineering

**Associate Director, Chemical Engineering**

*Nurix Therapeutics is a clinical stage biopharmaceutical company focused on the discovery, development, and commercialization of targeted protein degradation medicines, the next frontier in innovative drug design aimed at improving treatment options for patients with cancer and inflammatory diseases. Powered by a fully AI-integrated discovery engine capable of tackling any protein class, and coupled with unparalleled ligase expertise, Nurix’s dedicated team has built a formidable advantage in translating the science of targeted protein degradation into clinical advancements. Nurix aims to establish degrader-based treatments at the forefront of patient care, writing medicine’s next chapter with a new script to outmatch disease.*

**Position Description**

Nurix is seeking an experienced, independent, and highly motivated individual who will be accountable for end‑to‑end chemical engineering support of bexobrutideg (NX-5948) drug substance (DS) from late‑stage development through commercial launch, including oversight of external manufacturing sites. The Associate Director, Chemical Engineering will work closely with the CMC team and colleagues in cross-functional departments to provide scientific, technical, and hands-on leadership and oversight of facility and equipment operations at Contract Development Manufacturing Organizations (CDMOs) to support bexobrutideg drug substance manufacturing process optimization and scale-up. The position will report to the Director, Chemical Development.

Responsibilities will include but are not limited to:

- Provide engineering leadership to design, develop and optimize scalable routes for small-molecule DS manufacturing, including demonstrated knowledge in unit operation design, process modeling, process equipment selection and scale-up methodologies.
- Review equipment configurations, qualification packages, and maintenance records at CDMOs to ensure equipment trains are properly qualified, maintained and operating at optimal performance to support Nurix manufacturing operations.
- Oversee equipment engineering and scale-up operations at DS CDMOs, including hands‑on process troubleshooting during engineering, clinical, registration and PPQ batches.
- Lead technology transfer to CDMOs including scale-up and demonstration of new chemical processes in development and commercial equipment.
- Coordinate with CDMOs and Nurix Quality Assurance, and Global Supply Chain functions to ensure timely manufacture and release of DS lots.
- Partner within Nurix CMC to drive process understanding (critical process parameters, critical quality attributes, control strategy) using engineering principles, DoE and QbD concepts.
- Review and approve Master Batch Records, campaign reports, deviation investigations and change controls for drug substance operations.
- Ensure manufacturing operations adhere to company quality, safety and regulatory standards (FDA, EMA, ICH, cGMP).
- Provide regular Person-In-Plant support for DS manufacturing and ongoing performance monitoring of key facility and operational KPIs across manufacturing sites, including schedule adherence, batch performance, deviation trends, and inspection readiness.
- Author and review CMC sections of regulatory filings including INDs/IMPD, and NDA/MAA, including responses to Health Authority queries.
- Define and drive the long‑term engineering strategy for bexobrutideg DS, including process robustness, lifecycle management, and cost‑of‑goods optimization.
- Represent Chemical Engineering on CMC and cross‑functional program teams, providing input to development strategy, risk assessments, and timelines.
- Manage and provide technical mentorship of scientists and engineers.

**Required Qualifications**

- Ph.D. in chemical engineering, or related field with at least 5 years (M.S. with 10 years or B.S. with 15 years) of industrial, late-phase, small-molecule drug substance development experience
- Extensive knowledge and experience in GMP drug substance manufacturing, characterization, process development, equipment evaluation/selection, scale up and process validation.
- Knowledge of solid‑state properties, polymorphism, and crystallization principles relevant to small‑molecule drug substance.
- Extensive third-party drug substance CDMO management experience including tech transfer activities, QbD and DoE studies, clinical supply production, registration batch production and commercial launch activities.
- In-depth knowledge of relevant cGMP, ICH, FDA and EMA guidelines.
- Proven track record of effective internal and external collaboration.
- Excellent oral and written communication skills, interpersonal skills and problem-solving abilities.
- Ability to multi-task, manage conflict and work in a fast-paced environment.
- Ability to travel up to 25% of their time.

**Fit with Nurix Culture and Values**

- Strong team orientation; highly collaborative
- Solutions and results-oriented focus
- Hands-on approach; resourceful and open to diverse points of view

**Salary Range:** $189,800 - $216,700

**Location:**  Brisbane, CA - Onsite

California

Associate Director, Commissioning and Start-Up Engineering (HAZOP)

Company Description

**About AbbVie**

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at [www.abbvie.com](<http://www.abbvie.com/>). Follow @abbvie on [LinkedIn,](<https://www.linkedin.com/company/abbvie/>) [Facebook](<https://www.facebook.com/AbbVieGlobal/>), [Instagram](<https://www.instagram.com/abbvie/>), [X](<https://twitter.com/abbvie>) and [YouTube.](<https://www.youtube.com/user/AbbVie>)

Job Description

The Associate Director, Commissioning and Start-Up is responsible for providing operational leadership for commissioning, qualification, and start-up activities supporting new manufacturing sites, facilities expansion, utilities, equipment, and related systems. This role ensures assets are delivered safely, compliantly, and on schedule in a state of readiness for GMP operations, while meeting Abbvie quality, operational, and business objectives. The Associate Director leads cross-functional teams and external partners while enabling a smooth transition from project execution to sustained operational performance.

**Key Responsibilities:**

- Provide leadership for commissioning, qualification, and start-up activities across facilities, utilities, equipment, and supporting systems.
- Develop program strategy and lead detailed execution of Hazard and Operability (HAZOP) Studies for all capital programs.
- Develop, align, and execute commissioning and start-up strategies, plans, schedules, protocols, and turnover packages.
- Ensure readiness of systems for GMP operations in compliance with applicable regulatory, quality, safety, and company standards.
- Partner cross-functionally with engineering, validation, manufacturing, quality, EHS, automation, project management, and third-party contractors to deliver integrated startup execution.
- Manage risks, dependencies, timelines, budgets, and issue resolution throughout the project lifecycle.
- Support and oversee site walkdown processes against as built Piping & Instrumentation Diagrams along with Equipment installations to ensure accuracy and operational readiness.
- Lead troubleshooting and corrective action efforts during startup to support successful implementation and stable operations.
- Lead operational readiness and the successful integration of new assets into routine site operations.
- Support budgeting, resource planning, for commissioning and start-up efforts.

Qualifications

- Bachelor’s degree in Engineering, Pharmaceutical Sciences, Life Sciences, or a related technical discipline required; advanced degree preferred.
- Typically, 10-12 years20+ years of relevant experience in pharmaceutical or biotech manufacturing and engineering or other highly regulated manufacturing environments.
- Broad experience in commissioning, qualification, start-up, validation, or operational readiness.
- Demonstrated experience leading cross-functional teams. Ability to manage multiple priorities, work through ambiguity, and drive execution in a matrixed organization.
- Strong track record of delivering results in a GMP-regulated environment.
- Strong project leadership, organizational, and communication skills.
- Ability to influence and drive alignment across functions and business units.

**Preferred Qualifications:**

- Experience supporting facility expansions, new product introductions, or major capital projects.
- Experience in sterile injectables, biologics, API, or oral solid dose manufacturing.
- Experience with risk-based CQV methodology and digital turnover systems.
- Prior people leadership experience in a matrixed, global, or highly collaborative environment.

**Leadership Competencies:**

- Strategic leadership
- Enterprise Mindset
- Cross-functional influence
- Accountability and decision-making
- Change leadership
- Operational excellence
- Compliance and quality focus

**Work Environment:** This role may require travel to project and manufacturing sites and extended hours during critical commissioning and start-up phases.

**Key internal stakeholders for an Associate Director of Commissioning and Plant Start-Up typically include:**

- Site Leadership and Site Director – overall site strategy, priorities, and operational readiness
- Engineering Leadership through Director and VP – design execution, utilities, facilities, and project delivery
- Validation / CQV Team – commissioning, qualification, and validation strategy and execution
- Quality Assurance leadership thru Director Level – cGMP compliance, documentation, and release readiness
- EHS (Environmental, Health & Safety) thru Director and VP Level – safe startup, risk controls, and compliance
- Automation / IT / Digital Systems – control systems, data integrity, MES, and infrastructure readiness
- Maintenance / Reliability (MEP) Team – asset readiness, PM strategy, spares, and maintainability
- Project Management / PMO Organization – schedule, scope, budget, and governance
- Procurement / Strategic Sourcing thru Director Level – contractor and vendor management
- HR / Talent / Learning – staffing, training, and organizational readiness
- Finance – budget tracking and capital spend governance

Additional Information

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:

- The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.
- We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.
- This job is eligible to participate in our long-term incentive programs.

Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.

US & Puerto Rico only - to learn more, visit [https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html](<https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html>)

US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:

[https://www.abbvie.com/join-us/reasonable-accommodations.html](<https://www.abbvie.com/join-us/reasonable-accommodations.html>)

Associate Director, Commissioning and Start-Up Engineering (BDS)

Company Description

**About AbbVie**

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at [www.abbvie.com](<http://www.abbvie.com/>). Follow @abbvie on [LinkedIn,](<https://www.linkedin.com/company/abbvie/>) [Facebook](<https://www.facebook.com/AbbVieGlobal/>), [Instagram](<https://www.instagram.com/abbvie/>), [X](<https://twitter.com/abbvie>) and [YouTube.](<https://www.youtube.com/user/AbbVie>)

Job Description

The Associate Director, Commissioning and Start-Up is responsible for providing operational leadership for commissioning, qualification, and start-up activities supporting new manufacturing sites, facilities expansion, utilities, equipment, and related systems. This role ensures assets are delivered safely, compliantly, and on schedule in a state of readiness for GMP operations, while meeting Abbvie quality, operational, and business objectives. The Associate Director leads cross-functional teams and external partners while enabling a smooth transition from project execution to sustained operational performance.

**Key Responsibilities**

- Provide leadership for commissioning, qualification, and start-up activities across facilities, utilities, equipment, and supporting systems.
- Develop program strategy and lead detailed execution of Hazard and Operability (HAZOP) Studies for all capital programs.
- Develop, align, and execute commissioning and start-up strategies, plans, schedules, protocols, and turnover packages.
- Ensure readiness of systems for GMP operations in compliance with applicable regulatory, quality, safety, and company standards.
- Partner cross-functionally with engineering, validation, manufacturing, quality, EHS, automation, project management, and third-party contractors to deliver integrated startup execution.
- Manage risks, dependencies, timelines, budgets, and issue resolution throughout the project lifecycle.
- Support and oversee site walkdown processes against as built Piping & Instrumentation Diagrams along with Equipment installations to ensure accuracy and operational readiness.
- Lead troubleshooting and corrective action efforts during startup to support successful implementation and stable operations.
- Lead operational readiness and the successful integration of new assets into routine site operations.
- Support budgeting, resource planning, for commissioning and start-up efforts.

Qualifications

**Qualifications:**

- Bachelor’s degree in Engineering, Pharmaceutical Sciences, Life Sciences, or a related technical discipline required; advanced degree preferred.
- Typically, 10-12 years20+ years of relevant experience in pharmaceutical or biotech manufacturing and engineering or other highly regulated manufacturing environments.
- Broad experience in commissioning, qualification, start-up, validation, or operational readiness.
- Demonstrated experience leading cross-functional teams. Ability to manage multiple priorities, work through ambiguity, and drive execution in a matrixed organization.
- Strong track record of delivering results in a GMP-regulated environment.
- Strong project leadership, organizational, and communication skills.
- Ability to influence and drive alignment across functions and business units.

**Preferred Qualifications**

- Experience supporting facility expansions, new product introductions, or major capital projects.
- Experience in sterile injectables, biologics, API, or oral solid dose manufacturing.
- Experience with risk-based CQV methodology and digital turnover systems.
- Prior people leadership experience in a matrixed, global, or highly collaborative environment.

**Leadership Competencies**

- Strategic leadership
- Enterprise Mindset
- Cross-functional influence
- Accountability and decision-making
- Change leadership
- Operational excellence
- Compliance and quality focus

**Work Environment:** This role may require travel to project and manufacturing sites and extended hours during critical commissioning and start-up phases.

**Key internal stakeholders for an Associate Director of Commissioning and Plant Start-Up typically include:**

- Site Leadership and Site Director – overall site strategy, priorities, and operational readiness
- Engineering Leadership through Director and VP – design execution, utilities, facilities, and project delivery
- Validation / CQV Team – commissioning, qualification, and validation strategy and execution
- Quality Assurance leadership thru Director Level – cGMP compliance, documentation, and release readiness
- EHS (Environmental, Health & Safety) thru Director and VP Level – safe startup, risk controls, and compliance
- Automation / IT / Digital Systems – control systems, data integrity, MES, and infrastructure readiness
- Maintenance / Reliability (MEP) Team – asset readiness, PM strategy, spares, and maintainability
- Project Management / PMO Organization – schedule, scope, budget, and governance
- Procurement / Strategic Sourcing thru Director Level – contractor and vendor management
- HR / Talent / Learning – staffing, training, and organizational readiness
- Finance – budget tracking and capital spend governance

Additional Information

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:

- The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.
- We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.
- This job is eligible to participate in our long-term incentive programs.

Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.

US & Puerto Rico only - to learn more, visit [https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html](<https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html>)

US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:

[https://www.abbvie.com/join-us/reasonable-accommodations.html](<https://www.abbvie.com/join-us/reasonable-accommodations.html>)

Director, Engineering, Technical Expert Sterile Fill

Company Description

**About AbbVie**

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at [www.abbvie.com](<http://www.abbvie.com/>). Follow @abbvie on [LinkedIn,](<https://www.linkedin.com/company/abbvie/>) [Facebook](<https://www.facebook.com/AbbVieGlobal/>), [Instagram](<https://www.instagram.com/abbvie/>), [X](<https://twitter.com/abbvie>) and [YouTube.](<https://www.youtube.com/user/AbbVie>)

Job Description

**Position Summary**

The Director Engineering Technical Expert Sterile Fill provides enterprise-level technical leadership for sterile fill engineering across AbbVie’s strategic investment portfolio, with accountability for biologics sterile filling, Annex 1-aligned contamination control, aseptic processing design, barrier technology strategy, equipment / facility interfaces, GMP readiness, validation / CQV integration and technical assurance within Strategic Investments - Engineering.

The role shapes and governs engineering strategies for strategic investments by setting technical direction, aligning standards and assuring robust execution across priority capital programs, technology platforms and future manufacturing capabilities.

The role leads engineering activities associated with strategic investment programs, including new facility investments, technology platform deployments, capacity expansion, infrastructure enablement, lifecycle asset renewal and capability-building initiatives that materially impact long-term business performance.

The role partners with Strategic Investments leadership, operating sites, quality, EHS, validation / CQV and external engineering partners to make high-quality technical decisions, resolve complex risks and deliver business-aligned engineering outcomes.

Strategic Investments - Engineering Context

Strategic Investments - Engineering provides senior technical leadership, engineering governance, standards ownership and execution assurance across AbbVie’s strategic investment portfolio.

The organization supports strategic capital programs including new manufacturing facilities, technology platform deployments, capacity expansion, infrastructure enablement, lifecycle asset renewal and future capability investments.

Strategic Investments - Engineering roles are expected to establish clear technical direction, drive enterprise alignment, transfer lessons learned and enable consistent, high-quality engineering delivery across the strategic investment portfolio.

**Key Responsibilities**

**Strategic Investments - Engineering Governance and Standards**

- Establish, maintain and deploy global engineering standards, technical practices and governance expectations for biologics sterile fill engineering, Annex 1-aligned contamination control strategy, aseptic processing, barrier technologies, equipment / facility interfaces, GMP readiness, validation / CQV integration and technical assurance.
- Drive consistent application of technical standards, design principles, lessons learned and engineering playbooks across regions, sites and capital projects.
- Ensure discipline strategies directly support AbbVie’s strategic investment priorities, future manufacturing capability requirements and major capital program objectives.
- Provide governance and escalation for technical decisions with material safety, quality, compliance, cost, schedule, operability or lifecycle impact.

**Strategic Investment Leadership and Execution Support**

- Provide senior engineering leadership for strategic capital investments, including new facility builds, technology platform deployments, capacity projects, infrastructure enablement, lifecycle asset renewal and future capability investments.
- Support front-end engineering, facility concept development, investment option evaluation, manufacturing capability assessments and site / platform planning activities.
- Partner with Strategic Investments and project leadership to ensure technical assumptions, deliverables, risks and resource needs are integrated into capital program plans.
- Apply enterprise lessons learned and strategic investment standards to improve project quality, decision speed, reliability and readiness across the portfolio.

**Sterile Filling, Biologics Manufacturing and Annex 1 Compliance**

- Provide senior technical leadership for sterile filling of biologics and parenteral products, including vial, syringe, cartridge and bulk sterile transfer interfaces where relevant to strategic investment scope.
- Ensure facility, equipment and process design decisions are aligned with EU GMP Annex 1 expectations for sterile medicinal products, including contamination control strategy, quality risk management, cleanroom classification, barrier technology and aseptic process control.
- Govern technical strategy for isolators, restricted access barrier systems, Grade A critical zones, Grade B / C / D background environments, unidirectional airflow, first-air protection, glove systems, transfer systems and aseptic interventions.
- Lead engineering input to contamination control strategy development, ensuring critical control points are embedded across facility design, equipment, utilities, personnel flows, material flows, cleaning, disinfection, environmental monitoring and maintenance access.
- Partner with Quality, MS&T, Validation / CQV and Operations to ensure aseptic process simulations, media fill strategy, filter integrity testing, sterile filtration, container closure integrity, environmental monitoring and viable / non-viable particle control are considered in design and readiness decisions.
- Provide technical challenge and risk-based decision support for interventions, line set-up, lyophilization interfaces, stopper / component handling, depyrogenation, sterilization, single-use systems, CIP / SIP interfaces and biologics product protection requirements.
- Ensure sterile fill investment programs are designed for inspection readiness, robust contamination prevention, operational maintainability, product sterility assurance and reliable long-term biologics manufacturing performance.

**Technical Leadership and Delivery**

- Lead technical decision-making for biologics sterile fill engineering, aseptic processing design, Annex 1 compliance expectations, contamination control strategy, barrier technology selection, equipment / facility interfaces, GMP readiness, validation / CQV integration and technical assurance across strategic investment programs and technology platforms.
- Ensure engineering deliverables support safety, quality, compliance, operability, maintainability, reliability, sustainability and operational readiness.
- Coordinate technical input from project teams, site SMEs, external engineering partners, vendors and cross-functional stakeholders.
- Drive timely resolution of technical issues and ensure disciplined escalation when decisions have material project, portfolio, enterprise or business impact.

**Cross-Functional Integration**

- Partner with Strategic Investments, manufacturing operations, quality, validation / CQV, EHS, site engineering, MS&T, supply chain, finance and related engineering disciplines.
- Ensure discipline decisions are integrated with strategic investment objectives, manufacturing strategy, capacity planning, technology platform deployment, regulatory expectations and site handover needs.
- Facilitate collaboration across regions, sites and project teams to avoid fragmented solutions and drive consistency across strategic investments.
- Represent Strategic Investments - Engineering in technical reviews, project forums and risk discussions relevant to assigned scope.

**Capability Building and Continuous Improvement**

- Share engineering best practices, lessons learned and technical knowledge across sites, regions and projects.
- Build capability through coaching, mentoring, technical review discipline and development of reusable engineering practices.
- Promote a culture of engineering excellence, safety, quality, reliability, collaboration, accountability and proactive risk management.
- Support continuous improvement of Strategic Investments - Engineering standards, templates, knowledge management and project delivery approaches.

**Strategic Investments - Engineering Leadership Expectations**

- Collaborate across the enterprise engineering community to identify, develop and deploy best practices, technical standards, lessons learned and capability-building initiatives.
- Promote consistency, quality, reliability, sustainability and project delivery performance across the strategic investment portfolio.
- Support long-range strategic investment planning, manufacturing strategy and future capability development.
- Build technical capability through coaching, mentoring, standards governance, knowledge management and cross-functional collaboration.

**Stakeholder Interfaces**

**Strategic Investments:** Investment planning, portfolio alignment, technical assumptions, front-end engineering, strategic capital program support and executive decision enablement.

**Manufacturing Sites and Operations:** Network needs, site readiness, operability, maintainability, startup, handover and operational performance support.

**Quality, Validation / CQV and EHS:** Compliance expectations, validation strategy, qualification readiness, safety, risk review and inspection readiness interfaces.

**Strategic Investments - Engineering Disciplines:** Cross-discipline technical integration, standards, design reviews, technical issue resolution and strategic investment lessons learned.

**External Engineering Partners, EPCM Firms, Vendors and OEMs:** Technical oversight, deliverable review, issue escalation, supplier alignment and execution quality.

Qualifications

- Bachelor’s degree in Engineering, Science or a relevant technical discipline required; advanced degree preferred where relevant.
- Typically 12+ to 15+ years of relevant engineering, manufacturing, capital project, technical operations or regulated manufacturing experience.
- Demonstrated technical capability in biologics sterile filling, aseptic processing, Annex 1 contamination control expectations, isolators / RABS, cleanroom interfaces, sterile filtration, environmental monitoring, GMP readiness, validation / CQV integration and technical assurance.
- Experience supporting pharmaceutical, biopharmaceutical, medical device, API, peptides, biologics, sterile or similarly regulated manufacturing environments preferred.
- Demonstrated ability to operate across global functions, strategic investment teams, manufacturing sites, project teams, suppliers, vendors and external engineering partners.
- Strong communication, risk management, technical judgment, stakeholder engagement and structured problem-solving skills.

**Technical Competencies**

- Biologics sterile fill-finish systems
- EU GMP Annex 1 contamination control strategy, aseptic processing and sterility assurance
- Equipment / facility interfaces
- Strategic investment portfolio support
- Strategic investment manufacturing readiness and sterile operations support
- Strategic capital investment leadership
- Engineering governance and standards
- Technical risk management
- Project execution support
- Stakeholder management
- Vendor / partner technical coordination
- GMP and regulated manufacturing awareness
- Isolator / RABS design, Grade A critical zones, background classification and aseptic intervention strategy
- Operational readiness and handover support

**Leadership Competencies**

- Strategic thinking and enterprise mindset
- Matrix leadership and influence without direct authority
- Clear technical communication and executive-ready recommendations
- Risk-based decision making and issue escalation
- Collaboration across functions, sites, regions and external partners
- Capability building, mentoring and knowledge sharing
- Continuous improvement and commitment to safety, quality and compliance

**Working Relationships**

This role works globally with Strategic Investments, Strategic Investments - Engineering disciplines, manufacturing sites, quality, validation / CQV, EHS, operations, MS&T, supply chain, finance, external engineering firms, technology vendors and equipment suppliers. The role is expected to operate as a senior technical leader across multiple strategic investment programs and technology platforms, setting direction, strengthening technical governance and enabling high-quality capital delivery.

Additional Information

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:

- The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.
- We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.
- This job is eligible to participate in our long-term incentive programs.

Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.

US & Puerto Rico only - to learn more, visit [https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html](<https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html>)

US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:

[https://www.abbvie.com/join-us/reasonable-accommodations.html](<https://www.abbvie.com/join-us/reasonable-accommodations.html>)

Director, Engineering, Utilities & Electrical

Company Description

**About AbbVie**

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at [www.abbvie.com](<http://www.abbvie.com/>). Follow @abbvie on [LinkedIn,](<https://www.linkedin.com/company/abbvie/>) [Facebook](<https://www.facebook.com/AbbVieGlobal/>), [Instagram](<https://www.instagram.com/abbvie/>), [X](<https://twitter.com/abbvie>) and [YouTube.](<https://www.youtube.com/user/AbbVie>)

Job Description

**Position Summary**

The Director, Utilities & Electrical owns strategic discipline leadership, people leadership, technical governance and project enablement for electrical power systems, clean utilities, black utilities, energy infrastructure, reliability, maintainability, electrical safety and operational readiness within AbbVie Global Engineering.

The role provides senior technical and organizational leadership for AbbVie’s global manufacturing network and strategic capital investments through standards ownership, front-end engineering support, technical decision-making, project risk management and disciplined execution across priority investment programs, manufacturing sites and technology platforms.

The Director leads and develops a global team of electrical and utilities technical experts, establishes clear priorities and accountabilities, and ensures the organization has the capability and capacity required to support brownfield expansions, modernization programs, debottlenecking, infrastructure upgrades, lifecycle asset replacement and greenfield manufacturing investments.

The role serves as the senior Global Engineering authority for electrical and utilities strategy, ensuring systems are safe, compliant, resilient, energy efficient, maintainable and capable of supporting current and future manufacturing requirements.

The Director partners with Strategic Investments, project delivery teams, operations, quality, EHS, validation/CQV, site engineering, sustainability, digital/automation and external engineering partners to deliver technically robust, scalable and business-aligned engineering solutions.

**Global Engineering Governance and Standards**

- Establish, own and deploy global engineering standards, design criteria, specifications, technical practices and governance expectations for electrical power systems, clean utilities, black utilities, energy infrastructure, reliability, maintainability and electrical safety.
- Act as the senior discipline authority for material electrical and utilities decisions affecting safety, quality, compliance, cost, schedule, operability, resilience or lifecycle value.
- Define discipline strategy and multiyear capability roadmaps aligned with AbbVie’s manufacturing network strategy, sustainability objectives and strategic investment priorities.
- Govern consistent application of standards, design principles, lessons learned and engineering playbooks across regions, sites and capital projects.
- Establish assurance and review processes that verify technical quality at key project stage gates.
- Lead resolution and escalation of significant discipline risks, deviations from standards and cross-project technical issues.
- Represent Global Engineering in enterprise technical governance forums and communicate clear, executive-ready recommendations to senior stakeholders.

**Strategic Capital Investment Leadership**

- Provide senior owner-side engineering leadership for the electrical and utilities scope of strategic capital investments, including new facilities, major capacity programs, technology platform deployments, infrastructure solutions and lifecycle asset strategies.
- Lead discipline input to front-end engineering, facility concepts, site master planning, investment option evaluation, business cases and technology selection.
- Define electrical and utilities design strategies for strategic projects, including power architecture, utility generation and distribution, redundancy philosophy, capacity planning, energy performance, maintainability, monitoring and operational readiness.
- Ensure discipline assumptions, deliverables, risks, interfaces, resources and decisions are incorporated into program plans, cost estimates and execution strategies.
- Establish project assurance priorities and direct senior technical reviews at concept, basic design, detailed design, construction, commissioning and handover stages.
- Balance safety, quality, compliance, reliability, sustainability, cost and schedule when making or recommending investment decisions.
- Apply global lessons learned and network standards to improve project quality, speed, predictability and readiness across the portfolio.
- Provide clear escalation to the VP, Global Engineering and Strategic Investments leadership when decisions have material enterprise, program or network impact.

**Electrical and Utilities Technical Leadership**

- Lead technical decision-making for medium- and low-voltage power distribution, substations, transformers, switchgear, motor control, emergency and standby power, uninterruptible power supplies, grounding, lightning protection and electrical protection systems.
- Provide governance for electrical safety, arc-flash risk, hazardous-area classification interfaces, protection coordination, power quality, system studies and safe equipment lifecycle management.
- Direct strategies for clean utilities, including purified water, water for injection, clean steam, process gases and associated generation, storage, distribution, monitoring and sanitization systems.
- Direct strategies for black utilities, including plant steam, chilled water, cooling water, compressed air, nitrogen, natural gas, wastewater and other supporting infrastructure.
- Set expectations for system capacity, redundancy, resilience, reliability, maintainability, energy efficiency and future expansion.
- Ensure electrical and utilities systems are appropriately integrated with process, HVAC, mechanical, civil, structural, automation, instrumentation and building-management systems.
- Oversee technical reviews of load lists, single-line diagrams, utility balances, capacity models, equipment specifications, vendor packages, design calculations and commissioning strategies.
- Ensure engineering deliverables support GMP compliance, validation/CQV, safe operation, maintainability, sustainability and effective site handover.
- Drive timely resolution of complex technical issues and ensure decisions are documented, risk assessed and communicated.

**People Leadership and Organizational Capability**

- Lead, develop and retain a high-performing global team of electrical, clean-utilities and black-utilities technical experts.
- Set clear direction, priorities, objectives and performance expectations aligned with Global Engineering and Strategic Investments priorities.
- Allocate technical resources across programs and sites based on business criticality, project risk, specialist capability and portfolio demand.
- Coach and mentor technical leaders and subject-matter experts, strengthening technical judgment, leadership capability and succession readiness.
- Establish structured development plans, knowledge-transfer mechanisms and succession plans for critical electrical and utilities capabilities.
- Build an inclusive, accountable and collaborative culture focused on engineering excellence, safety, quality and reliable delivery.
- Clarify decision rights and interfaces between Global Engineering, site engineering, project teams and external partners.
- Use external engineering partners and specialist resources strategically while retaining effective owner-side knowledge and governance.

**Portfolio, Delivery and Partner Governance**

- Provide discipline oversight across multiple concurrent projects, manufacturing sites and technology platforms.
- Establish portfolio-level visibility of significant technical decisions, design maturity, risks, resource constraints and assurance findings.
- Work with project leadership to define discipline deliverables, review schedules, staffing needs and escalation routes.
- Hold external engineering partners, EPCM firms, vendors and OEMs accountable for technical quality, standards compliance and timely resolution of issues.
- Support sourcing strategies, framework agreements, vendor qualification and technical bid evaluations for key electrical and utilities equipment and services.
- Review supplier performance and lead corrective action where technical quality, schedule, documentation or execution does not meet expectations.
- Ensure effective transition from project delivery to commissioning, qualification, operational readiness and sustained manufacturing support.
- Promote predictable delivery through standardization, reusable designs, disciplined change control and early risk identification.

**Cross-Functional and Enterprise Leadership**

- Partner with Strategic Investments, manufacturing operations, quality, validation/CQV, EHS, site engineering, MS&T, supply chain, finance, procurement, sustainability, digital/automation and related engineering disciplines.
- Ensure electrical and utilities decisions are integrated with manufacturing strategy, network capacity, regulatory expectations, technology deployment and site handover requirements.
- Influence senior stakeholders across functions, regions and sites to achieve aligned enterprise outcomes.
- Facilitate collaboration across projects and sites to prevent fragmented solutions and unnecessary technical variation.
- Represent Global Engineering in technical reviews, investment forums, risk discussions and program governance relevant to the assigned scope.
- Communicate complex technical matters in clear business terms, including implications for safety, compliance, investment, schedule, resilience and lifecycle performance.

**Global Engineering Leadership Expectations**

- Operate with an enterprise mindset and make decisions that optimize outcomes across the manufacturing network rather than for an individual project or site.
- Translate business and manufacturing strategies into discipline priorities, technical roadmaps and executable plans.
- Demonstrate visible leadership for safety, quality, compliance, integrity and engineering excellence.
- Provide clear direction in ambiguous or high-risk situations while appropriately engaging specialists and senior stakeholders.
- Build trusted relationships with executives, site leaders, project leaders and external partners.
- Develop organizational capability through coaching, performance management, succession planning and intentional deployment of talent.
- Challenge technical assumptions constructively and ensure important risks and trade-offs are transparent.
- Promote standardization, innovation, sustainability, knowledge sharing and continuous improvement across the global network.
- Hold teams and partners accountable for commitments, technical quality and timely delivery.

Qualifications

- Bachelor’s degree in Electrical Engineering or a closely related engineering discipline required; master’s degree or relevant professional qualification preferred.
- Typically 15 or more years of progressive experience in electrical engineering, utilities engineering, manufacturing engineering, capital projects or technical operations, including significant leadership responsibility.
- Extensive experience in pharmaceutical, biopharmaceutical, API, peptide, biologics, sterile or similarly regulated manufacturing environments.
- Demonstrated experience leading electrical and utilities engineering scope for major brownfield and greenfield capital investments.
- Proven experience leading and developing technical professionals, establishing priorities, managing performance and building organizational capability.
- Demonstrated ability to direct multiple projects, sites, workstreams and external engineering partners in a global matrix organization.
- Strong technical knowledge of industrial electrical power distribution, emergency power, electrical safety, reliability, power-system studies, clean utilities and black utilities.
- Working knowledge of GMP, EHS, validation/CQV, commissioning, operational readiness and regulated asset lifecycle requirements.
- Strong commercial and financial acumen, with the ability to assess technical alternatives, lifecycle value, capital cost, operating cost and business risk.
- Demonstrated ability to make risk-based decisions, influence senior stakeholders and provide concise executive recommendations.
- Experience governing EPCM firms, design partners, equipment vendors, utilities specialists and construction or commissioning organizations.
- Strong communication, negotiation, stakeholder management, talent development and structured problem-solving skills.
- Ability to travel globally to manufacturing sites, engineering partners, suppliers and strategic project locations as required.

**Technical Competencies**

- Medium- and low-voltage power distribution
- Substations, transformers, switchgear and motor-control systems
- Emergency power, standby generation and uninterruptible power supplies
- Grounding, lightning protection, electrical protection and coordination
- Electrical safety, arc-flash risk and hazardous-area interfaces
- Power quality, load studies, capacity planning and system resilience
- Clean utilities generation, storage, distribution and monitoring
- Black utilities generation and distribution
- Utility balances, redundancy philosophies and lifecycle strategies
- Energy efficiency, sustainability and infrastructure decarbonization
- Reliability, maintainability and asset-management strategy
- GMP engineering, validation/CQV and operational readiness
- Global engineering standards and design governance
- Front-end engineering and strategic capital investment support
- Vendor, EPCM and external engineering-partner governance
- Technical risk management and executive decision support

**Leadership Competencies**

- Enterprise and strategic leadership
- Direct and matrix people leadership
- Talent development, succession planning and performance management
- Portfolio prioritization and resource deployment
- Executive communication and influence
- Risk-based decision-making
- Accountability for technical and project outcomes
- Cross-functional and global stakeholder leadership
- Partner and supplier governance
- Change leadership and organizational capability building
- Financial and commercial judgment
- Commitment to safety, quality, compliance and continuous improvement

Additional Information

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:

- The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.
- We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.
- This job is eligible to participate in our long-term incentive programs.

Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.

US & Puerto Rico only - to learn more, visit [https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html](<https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html>)

US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:

[https://www.abbvie.com/join-us/reasonable-accommodations.html](<https://www.abbvie.com/join-us/reasonable-accommodations.html>)

Manager Engineering (12 Hour Shift - 6AM to 6PM)

**Join Amgens Mission of Serving Patients**

At Amgen, if you feel like youre part of something bigger, its because you are. Our shared missionto serve patients living with serious illnessesdrives all that we do.

Since 1980, weve helped pioneer the world of biotech in our fight against the worlds toughest diseases. With our focus on four therapeutic areas Oncology, Inflammation, General Medicine, and Rare Disease we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, youll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, youll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Engineering Manager

**What you will do**

Lets do this. Lets change the world. In this role, the Manager of Engineering is responsible for maintenance support assignments at Amgens manufacturing site in Ohio. The position is a key role in the Engineering group and the candidate must manage and/or apply extensive technical expertise in the coordination of multiple, sophisticated, non-routine maintenance tasks of systems.

**Engineering & Maintenance Management**

- Key responsibilities will include providing engineering and maintenance services and support to pharmaceutical packaging lines.

- Lead a team of experienced maintenance and engineering personnel across Amgen commercial operations for product assembly, label, and packaging.

- The position is expected to bring to bear this team to support equipment maintenance, trouble shooting, triages, and process improvements.

- Ensure on-the-floor support of engineering and maintenance to reduce production downtime. Provide leadership and technical expertise for maintenance strategy for equipment and systems.

- Recommend and support improving maintenance instructions, including but not limited to Job Plans, Spare Parts Lists and PMs.

- Own selected maintenance SOPs and recommend and implement improvements. Recommend and implement improvements to the timing and coordination of maintenance activities. Provide field support to identify and resolve equipment and maintenance-related issues.

- Provide support to improve safety, compliance, efficiency, and effective execution of maintenance work orders.

- Evaluate equipment and instrumentation maintenance and failure history and recommend and implement improvements.

- Manage selected maintenance contract service providers.

- The Engineering Manager is tasked with facilitating effective communication across the Amgen commercial site network by utilizing all collaborators and delivering on technical improvements.

- Site communication will occur during daily Tier meetings, escalation processes, and vendor coordination, among other methods, to engage all team members and achieve technical advancements in communication, etc.

- This position requires the application of diverse and advanced engineering and scientific principles in support of commercial GMP Final Drug Product (FDP) operations in the Amgen Ohio manufacturing facility.

The Engineering Manager position works with the Senior Manager of Engineering at the Amgen Ohio facility.

The position is expected to travel approximately 15%.

**What we expect of you**

We are all different, yet we all use our unique contributions to serve patients. The professional we seek will possess these qualifications.

**Basic Qualifications:**

- Masters degree in e**n**gineering or related discipline & 3 years of related experience

- Bachelors degree in engineering or related discipline & 5 years of related experience

- Associate degree in Engineering or related discipline & 10 years of related experience

- High school diploma / GED & 12 years of related experience

In addition to meeting at least one of the above requirements, you must have experience directly managing people and/or leadership experience leading teams, projects, programs, or directing the allocation or resources. Your managerial experience may run concurrently with the required technical experience referenced above

**Preferred Qualifications:**

- Educational background in Mechanical Engineering, Mechatronics, or related technical degree

- Experience repairing mechanical equipment in a manufacturing environment (experience with packaging equipment preferred)

- Strong mechanical proficiency and trouble shooting skills

- Understanding in PLC, Computer Serialization, Packaging Equipment, Vision Inspection System (Cognex Vision System and Systech Serialization)

- Excellent organizational, project management, problem solving and technical writing capability

- Strong communication: verbal / written, collaboration, influencing and facilitation

- MS Office: Word, Excel, Power Point

**What you can expect of us**

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, well support your journey every step of the way.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:

- A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
- A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
- Stock-based long-term incentives
- Award-winning time-off plans
- Flexible work models, including remote and hybrid work arrangements, where possible

**Apply now**

**for a career that defies imagination**

Objects in your future are closer than they appear. Join us.

**careers.amgen.com**

**Sponsorship**

Sponsorship for this role is not guaranteed.

In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

Manager Engineering - (12 Hour Shift - 6PM to 6AM)

Senior Manager, Value & Access Insights Cross Portfolio Innovation

**Join Amgens Mission of Serving Patients**

At Amgen, if you feel like youre part of something bigger, its because you are. Our shared missionto serve patients living with serious illnessesdrives all that we do.

Since 1980, weve helped pioneer the world of biotech in our fight against the worlds toughest diseases. With our focus on four therapeutic areas Oncology, Inflammation, General Medicine, and Rare Disease we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, youll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, youll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

**Senior Manager, Value & Access Insights Cross Portfolio Innovation**

**Live**

**What you will do**

Lets do this. Lets change the world.

In an increasingly complex U.S. health care environment, generating compelling evidence of value and translating that evidence into effective access strategies are critical to helping patients access our medicines. The U.S. Value & Access (V&A) Insights team enables these strategies by integrating data, advanced analytics, and business expertise to inform payer and provider engagement, pricing, and contracting decisions.

The Senior Manager, Value & Access Insights Value Evidence & Contracting Innovation will lead two complementary areas of work across the U.S. portfolio. First, this individual will shape and deliver analytics-based value-evidence strategies that address priority payer questions and strengthen the evidence used in access discussions. Second, the Senior Manager will accelerate the development, adoption, and impact of innovative tools and analytical approaches for payer and provider contracting.

This is a high-visibility individual-contributor role requiring strong business judgment, analytical leadership, cross-functional influence, and the ability to move innovative capabilities from concept through deployment, adoption, and continuous improvement. The position reports to the Director, Value & Access Insights.

**Flexible Commuter role to Thousand Oaks, CA site. You will work on-site 2 days a week.**

**Key Responsibilities**

**Lead cross-portfolio value-evidence strategy -** Partner with V&A, brand, Health Economics and Outcomes Research (HEOR), Medical, and other cross-functional stakeholders to identify priority payer evidence needs, define analytics-based evidence strategies, and develop plans that address the clinical, economic, access, and population-level questions most relevant to payer decision-making.

**Identify evidence gaps and scalable opportunities -** Assess existing evidence and analytical capabilities across brands, identify common payer questions and evidence gaps, and establish reusable frameworks, methodologies, and data assets that improve consistency, speed, and quality across the portfolio.

**Advance innovative contracting capabilities** - Identify, evaluate, and scale innovative tools and analytical approaches that improve payer and provider contracting decisions. Translate business needs into use cases, requirements, workflows, and adoption plans in partnership with Contracting & Pricing, Finance, Market Access, brand teams, and Digital Technology & Innovation (DTI)/IT

**Own and evolve priority analytics products -** Lead the business and analytics roadmaps for Contracting IQ (CIQ), Price Elasticity Predictor (PEP AI), and other priority capabilities. Guide solution design, integration, testing, deployment, documentation, model monitoring, and continuous improvement, with an emphasis on explainability, usability, and measurable business impact.

**Drive adoption and capability building -** Develop practical workflows, training, documentation, and change-management approaches that embed new tools and methods into business decisions. Establish success measures, monitor use and impact, gather feedback, and continuously refine capabilities based on stakeholder needs.

**Ad hoc contracting and pricing support:** Support priority ad hoc analyses and delivery needs related to payer and provider contracting and pricing, including rapid-turn scenario assessments, bid and negotiation support, leadership requests, and development of decision-ready outputs.

**Cross-portfolio innovation and stakeholder partnership:** Support cross-portfolio innovation initiatives that strengthen decision support and ways of working for Contracting & Pricing (C&P), Market Access, CPE, and other key stakeholders; translate priority needs into scalable analytics and leadership-ready deliverables.

**Win**

**What we expect of you**

We are all different, yet we all use our unique contributions to serve patients. The strategic professional we seek is a motivated professional with these qualifications.

**Basic Qualifications**

PhD or foreign equivalent degree in Business Administration, Finance, Economics, Engineering, Computer Science, Data Science, Statistics, or a related field and 2 years of relevant experience

**OR**

Master's or foreign equivalent degree in Business Administration, Finance, Economics, Engineering, Computer Science, Data Science, Statistics, or a related field and 4 years of relevant experience

**OR**

Bachelor's or foreign equivalent degree in Business Administration, Finance, Economics, Engineering, Computer Science, Data Science, Statistics, or a related field and 6 years of relevant experience

**Preferred Qualifications**

5+ years of experience in the biopharmaceutical industry, health care analytics, market access, HEOR, and/or strategy consulting, with a strong understanding of the U.S. payer and provider landscape.

Demonstrated experience developing value-evidence strategies or analytics that support payer decision-making, access strategy, or customer engagement.

Experience leading analytical products or strategic workstreams from problem definition and solution design through deployment, adoption, impact measurement, and continuous improvement.

Strong analytical and problem-solving skills, with experience applying statistical and/or machine-learning methods to elasticity, segmentation, forecasting, optimization, or related business decisions.

Working proficiency with a combination of analytical and reporting tools, such as Python, SQL, Microsoft Excel, Anaplan, or business-intelligence platforms, and familiarity with pharmaceutical contracting, reimbursement, access, utilization, and financial data.

Strong written and oral communication skills, executive presence, and the ability to translate complex analytical findings into clear business implications and recommendations.

Demonstrated ability to collaborate across functions, influence without authority, manage multiple priorities, and maintain strong standards for data quality, documentation, and analytical rigor.

Amgen is committed to unlocking the potential of biology for patients suffering from serious illnesses by discovering, developing, manufacturing and delivering innovative human therapeutics. This approach begins by using tools like advanced human genetics to unravel the complexities of disease and understand the fundamentals of human biology.

We understand that to successfully sustain and grow as a global enterprise and deliver for patients - we must ensure a diverse and inclusive work environment.

Our culture is what makes Amgen a special place to work. We have a powerful shared purpose around our mission - to serve patients. We respect one another, recognize contributions, and have embedded collaboration, trust, empowerment and inclusion in all that we do.

We equip all our staff members to live well-rounded, healthy lives. Most recently, Amgen added benefits for transgender employees and continues to pride itself on industry-leading, family-friendly offerings for families of all compositions.

**Thrive**

**What you can expect from us**

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, well support your journey every step of the way.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:

- A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
- A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
- Stock-based long-term incentives
- Award-winning time-off plans and bi-annual company-wide shutdowns
- Flexible work models, including remote and hybrid work arrangements, where possible

**Apply now for a career that defies imagination**

**careers.amgen.com**

In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information.

Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

Sponsorship for this role is not guaranteed.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation. Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

Mfg Systems Engineer (DeltaV)

**Join Amgens Mission of Serving Patients**

At Amgen, if you feel like youre part of something bigger, its because you are. Our shared missionto serve patients living with serious illnessesdrives all that we do.

Since 1980, weve helped pioneer the world of biotech in our fight against the worlds toughest diseases. With our focus on four therapeutic areas Oncology, Inflammation, General Medicine, and Rare Disease we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, youll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, youll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

**Manufacturing Systems Engineer**

**What you will do**

Lets do this! Lets change the world! Amgen is seeking an Automation Engineer, internally known as a Manufacturing Systems Engineer, in our state-of-the-art Rhode Island facility to join the Automation Engineering team and who will report to the Mfg Systems Engineering Manager. In this vital role you will support complex and challenging process automation initiatives that require understanding of analytical problem-solving techniques, project management, lifecycle management and Operational Excellence. Additionally, the person is responsible for providing project leadership and daily operational support to the Automation Engineering team at the Amgen Rhode Island site.

Key Responsibilities Include:

- Provides technical support to commercial manufacturing, specific to process control, automation infrastructure, and process systems
- Works closely with multiple teams, including manufacturing, process engineering, utility operations, maintenance, quality assurance, and validation to manage a diverse portfolio of projects
- Leads and supports technical root cause analysis, incident investigations, and troubleshooting on process control issues related to electrical, instrumentation and control systems mainly rooted in DeltaV
- Supports new product introductions or new technology introductions by performing engineering assessments, implementing automation system configuration changes and supporting engineering runs
- Devises new approaches to complex problems through adaptations and modifications of standard automation technical principles
- Develop, organize, analyze, and present results for operational issues and engineering projects of small scope and complexity
- Communicates with multiple levels within the organization, highlighting issues and proposing solutions
- Supports capital project design review, commissioning, and qualification
- Applies automation engineering principles in the design, specification, construction, startup, and validation of process and GMP utilities equipment and systems for an array of projects of significant scope and complexity
- Provides technical support and issue resolution 24x7 on-call support of Automation systems on a rotational based frequency
- Applies experience and knowledge of industry best practices and tools to attain an innovative organization

**What we expect of you**

We are all different, yet we all use our unique contributions to serve patients. The automation engineering professional we seek is a dedicated teammate with these qualifications.

**Basic Qualifications:**

- High school diploma / GED and 8 years of automation and/or engineering experience OR
- Associates degree and 6 years of automation and/or engineering experience OR
- Bachelors degree and 2 years of automation and/or engineering experience OR
- Masters degree

**Preferred Qualifications:**

- Bachelors Degree related technical field
- 3+ years experience in Process Automation Engineering in a manufacturing support environment with at least 1+ year experience in the Pharmaceutical or Biotechnology industries
- 3+ years combined experience with the following product platforms: Emerson DeltaV DCS systems
- Familiarity with industry standards for batch control systems, software development life cycle methodologies, S88, 21 CFR Part 11, Validation, and GAMP
- Strong control system automation background. Design, installation, programming and validation of automated processes
- Experience with Mammalian Cell Culture, Protein Purification, Clean Utilities, CIP, SIP, Production Services and non-GMP Utilities preferred
- Experience with Tech Transfer, Process Design, and Commissioning
- Experience with validation and change control methodology

**What you can expect from us**

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, well support your journey every step of the way.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:

- A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
- A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
- Stock-based long-term incentives
- Award-winning time-off plans
- Flexible work models, including remote and hybrid work arrangements, where possible

**Apply now and make a lasting impact with the Amgen team.**

**careers.amgen.com**

In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information.

**Application deadline**

Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

**Sponsorship**

Sponsorship for this role is not guaranteed.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation. Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

Rhode Island

Undergrad Co-op DSTS Chemical Engineering - (January June 2027)

**Join Amgens Mission of Serving Patients**

At Amgen, if you feel like youre part of something bigger, its because you are. Our shared missionto serve patients living with serious illnessesdrives all that we do.

Since 1980, weve helped pioneer the world of biotech in our fight against the worlds toughest diseases. With our focus on four therapeutic areas Oncology, Inflammation, General Medicine, and Rare Disease we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, youll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, youll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

**Undergrad Co-op Drug Substance Technologies Synthetics Chemical Engineering - (January June 2027)**

**What You Will Do**

Lets do this. Lets change the world. During this program, you will use synthetic organic chemistry and chemical engineering principles to deliver robust processes and technologies for the manufacture of Active Pharmaceutical Ingredients (APIs) from early- to late-stage development, and serve our R&D, Clinical and Commercial partners. The Drug Substance Technologies Synthetics organization is principally concerned with translating developmental processes into commercial manufacturing reality through scientific expertise, innovative engineering, and deployment of manufacturing technologies.

The department at our Cambridge, Massachusetts location is looking for an Undergraduate student interested in a 6-month Co-op placement. The Co-op will learn the principles of process scale-up of small-molecule intermediates and active pharmaceutical ingredients using synthetic organic chemistry and chemical engineering principles. The Co-op will have an opportunity to interact with scientists and engineers implementing advanced manufacturing technologies for multiple product modalities. Relocation in the form of a transportation allowance will be provided for eligible candidates.

Program Eligibility Requirements

- Expected completion of one year of study from an accredited college or university prior to the co-op commencing
- Expected continued enrollment in an accredited college or university following the co-op program
- Student must be located in the United States for the duration of the co-op program
- Must be available to work a full-time schedule.

**What We Expect of You**

We are all different, yet we all use our unique contributions to serve patients. The passionate and driven individual weseekexemplifies the following qualifications:

**Basic Qualifications:**

Amgen requires that all individuals applying for an undergrad internship or a co-op assignment at Amgen must meet the following criteria:

- 18 years or older
- Currently enrolled in a full-time Bachelors Degree program from an accredited college or university with a 3.0 minimum GPA or equivalent

**Preferred Qualifications**

- Degree concentration(s) in Chemical Engineering, Chemistry and/or Data Sciences, with a focus or interest in organic synthesis and chemical engineering.
- Strong interpersonal, project management, analytical and quantitative skills
- Strong communication, interpersonal, organizational, project management, problem solving, analytical and quantitative skills
- Demonstrated personal initiative, self-motivation, flexibility, adaptability, and resourcefulness.
- Having experience in one of the listing areas below will be a plus: hands-on experience in the laboratory, flow chemistry, biocatalysis, lab automation, data analysis using Python.

**What You Can Expect of Us**

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, well support your journey every step of the way.

The base pay range for this opportunity in the U.S. is $28.87 per hour.

- Build a network of colleagues that will endure and grow throughout your time with us and beyond.
- Bring your authentic self to the table and become the professional youre inspired to be through accepting a culture that values the diversity of thought and experience and will flex to your strengths and possibilities.
- Participate in executive and social networking events, as well as community volunteer projects.

**Apply now and make a lasting impact with the Amgen team.**

**careers.amgen.com** Please search for Keyword R-255684

In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information.

**Application deadline**

Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

**Sponsorship**

Candidates must be authorized to work in the U.S. for the duration of this program. Sponsorship for future FTE roles is not guaranteed.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

Massachusetts

ProcessEngineer- CIP/ SIP/ Autoclave

**Join Amgens Mission of Serving Patients**

At Amgen, if you feel like youre part of something bigger, its because you are. Our shared missionto serve patients living with serious illnessesdrives all that we do.

Since 1980, weve helped pioneer the world of biotech in our fight against the worlds toughest diseases. With our focus on four therapeutic areas Oncology, Inflammation, General Medicine, and Rare Disease we reach millions of patients each year. As a member of the Amgen team, youll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, youll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Be part of Amgen's newest and most advanced drug substance manufacturing plant. When completed, the Amgen FleX batch facility will combine the latest in disposable technologies with traditional stainless steel equipment to allow for maximum flexibility in operations The FleX Batch facility will not only feature the best in-class drug substance manufacturing technologies with embedded industry 4.0 capabilities, but it will also integrate sustainability innovations to reduce carbon and waste, as part of Amgen's plan to be a carbon-neutral company by 2027.

**ProcessEngineer- CIP/ SIP/ Autoclave**

**What youwill do:**

In this vital role you will be joining the Facilities & Engineering (F&E) group to partner closely with the corporate engineering team to design, build, commission, and qualify new equipment and systems needed for drug substance production as well as developing domain expertise tosupport operations upon start-up.

Site design, construction, start-up, and operational readiness:

Support the commissioning and qualification ofmanufacturingsystems in alignment with GMP requirements and interact with regulatory inspectors.

- Demonstrate technical expertise and provide lifecycle support for CIP skid systems, SIP circuits, autoclaves, transfer panels, process tanks, valves, instrumentation, and associated automation platforms. The role will support commissioning, qualification, startup readiness, routine manufacturing operations, troubleshooting, and continuous improvement initiatives with a focus on CIP, SIP and autoclave systems.
- Ensuresystemsare installed andoperatesafelyandcomply withpertinent environmental health/safetypractice,rulesand regulations.
- Interact with regulatory inspectorsas a manufacturing systems owner to communicate anddemonstrateappropriate regulatorycomplianceofoperating systems.
- Assistwithnew product/technology introductions by performing engineering assessments,implementing equipment modifications, and supporting engineering runs.

**Site Operations:**

- Provide systemsupportforbiopharmaceutical process equipment specifically CIP/SIP and/or autoclave systems.Assistinidentifyingand implementing engineering-based improvements or upgrades to equipment or facility systems.
- Experience with CIP circuit design/validation and SIP
- Support the developmentofbusiness cases for improvements,identification ofdesign requirements, and translation ofthese requirements into process equipment/system design, specifications, and supporting the construction, startup, and validation ofimprovements.
- Develop equipment maintenance programs, ensure the availability of spare parts, andcoordinatemaintenance activities to ensure systems are in proper working order.

**What we expectofyou**

We are all different, yet we all use our unique contributions to serve patients. The engineering professional weseekenjoys challenges and is motivated to help serve patients with these qualifications.

**Basic Qualifications:**

Masters degree

OR

Bachelorsdegree and 2 years ofEngineeringexperience

OR

Associatesdegree and 6 years ofEngineeringexperience

OR

High school diploma / GED and 8 years ofEngineeringexperience

**Preferred Qualifications:**

- Bachelors degree in Chemical or Mechanical Engineeringor similarengineerdiscipline.

- 3+years'of relevant work experience with2+ years' experience in Biopharmaceuticaloperations/manufacturing environment

- Direct knowledge of design and troubleshooting with GMP Biopharmaceutical Production facility equipment/systems with direct experience with Solution Prep, Upstream, and Downstream purification equipment such as weigh and dispense equipment, solution preparation vessels, cell culture reactors, centrifugation, chromatography, viral filtration skids, and UFDF skids as well as other equipment needed to support these processes such as autoclaves, clean in place (CIP) systems, washers, clean steam, water for injection, etc.

- Ability to analyze problems, develop and propose engineering solutions in a scientificmanner using data-driven techniques and analyses (e.g., Data Analytics, Root CauseAnalysis (RCA), Statistical Process Control (SPC), Six Sigma, Predictive Maintenance, etc.)

- Experience working in a regulated environment (e.g.cGMP, OSHA, EPA, etc.) andfamiliarity with GMP quality systems/processes such as change control, non-conformances,corrective and preventative actions, and qualifications/validation

- Experience applying engineering principles to the design and implementation of systemmodifications, introduction of new processes, and the oversight of capital projects

- Understanding of capital projects in a GMP Biopharmaceutical Production facility includingprocurement, construction, startup, and validation

- Understanding ofsafety requirements working in a GMP Biopharmaceutical Productionfacility.

- Independent, ambitious, organized, able to multi-task in project environments, and skilled incommunication, facilitation, and teamwork

- Collaborativeteammateprepared to work in and embrace ateam basedenvironment thatrelies on communication for effective decision-making

- Strong leadership, technical writing, and communication/presentation skills

- Work schedule flexibility asrequiredto support 24/7 operations, requiring occasionalafterhoursengineering coverage

- Ability for domestic/international travel.

**What you can expect of us**

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, well support your journey every step of the way.

In addition to the base salary, Amgen offers competitive and comprehensive Total Rewards Plans that are aligned with local industry standards.

**Apply now and make a lasting impact with the Amgen team!**

**careers.amgen.com**

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

Civica Rx

Principal Engineer: Clean Utilities and HVAC (920)

**About Civica:**

Critical shortages of essential generic injectable drugs are an ongoing crisis in U.S. healthcare and have reached an all-time high. Over 300 essential medications are currently reported to be in shortage, according to industry and FDA reports.

Shortages put patients at risk and waste hospital resources.

Civica is a market-based nonprofit solution created in 2018 by health systems and philanthropies for the express purpose of preventing and mitigating drug shortages. Today, nearly 60 health systems have joined Civica, representing over 1,400 hospitals and approximately one-third of all U.S. hospital beds. Civica has also supplied the U.S. Department of Veteran’s Affairs, the U.S. Department of Defense and the U.S. Strategic National Stockpile with essential medicines. Civica currently supplies medicines to health system members in 49 states.

Civica’s mission has expanded beyond the hospital setting to reach consumers directly through CivicaScript, which is dedicated to making quality outpatient generic medicines affordable and available. CivicaScript works with trusted manufacturing partners to develop quality generic medicines and has forged partnerships with like-minded payors, pharmacy benefit managers and pharmacies to enable significant cost savings to be passed along to their customers.

Civica’s new 140,000 square foot state-of-the-art manufacturing facility in Virginia will soon produce a steady supply of more than three dozen sterile injectables, all drugs that are currently in or near shortage. The plant will also produce affordable biosimilar insulins, ensuring all Americans have access to lower cost, quality insulins, regardless of their insurance status.

The Civica Foundation is a 501(c)(3) organization that fosters philanthropic support for Civica’s work to manufacture and distribute affordable medications. The Foundation’s first commitment is to support Civica’s efforts to bring affordable insulin to all Americans. Leaders from nearly every corner of the diabetes ecosystem are partners in this initiative.

Civica is leading a movement for patients, not profits. Because eliminating shortages and stabilizing high prices are in the best interest of patients.

Join us. Learn more at [**www.civicarx.org**](<http://www.civicarx.org/>)

**Job Purpose**

The Principal Engineer: Utilities & HVAC is the site Subject Matter Expert (SME) for GMP HVAC and Critical Utility systems (WFI, Clean Steam, Process Compressed Air, and Nitrogen) and the ancillary support systems. This role will have specific responsibility in the final project phase of construction at our new site and after project start-up for site day-to-day operation.

This role will be responsible for reliable and cost-effective operation of the site's HVAC, Utilities, and ancillary systems associated with our new manufacturing facility in Petersburg, VA. It will be essential to maintain all these systems in a state of compliance, safety, control, and fit for use. This role will also drive continuous improvement initiatives and local capital investment.

**Major Accountabilities**

- SME with a deep technical expertise in all systems under his/her responsibility (GMP HVAC, GMP Utilities and ancillary systems associated within their facilities), understanding their applications in pharmaceutical manufacturing, well versed with flow charts and process parameters, and awareness of industry trends.
- Ensure the assigned processes are in alignment with the applicable regulatory Industry and Civica Standards.
- Support risk assessment exercises using the different tools available (eg.FMEA) and participate as required in teams, committees, or other groups and/or individually to achieve the departmental, site and/or company goals.
- Lead or participate in projects/changes for all the systems under his/her responsibility including design, verification activities (IV/OV/PQ), as user representative for capital projects or delivery agent for local projects.
- Develop the proper documentation (URs, Specification, test cases, etc..) to demonstrate that systems are properly installed, qualified and started up and that remains in a controlled state.
- Monitor utility systems and maintain KPI's to assure that they are operating properly, in compliance with requirements.
- Provide written instructions for the proper way to operate and maintain the equipment and process to assure that the system operates within the controlled parameters.
- Implement efficient and effective maintenance and reliability techniques.
- Apply problem solving skills by leading equipment failures, troubleshooting, demonstrating RCA lead investigator proficiency and guide operations personnel in the resolution of process issues.
- Provide customer consultation and notifications on issues that involve utilities areas. Assure that all necessary items are identified on the proper tracking systems, and make sure that items are completed by the required date.
- Provide technical assistance as necessary to maintenance, and operations personnel.
- Support internal and external inspections and investigations (including Quality and HSE).
- Maintain efficient communications with appropriate site customer groups.
- Proficiency with the DMS and CAPA systems.
- Maintain, develop, and conduct operations training of utility systems.
- Utilize statistical analysis tools to determine the process control, and capability for investigations.
- Participate in Process Hazard Review meetings and/or Safety Teams as required by leadership

**Education/Experience**

- Bachelor’s degree in engineering or relevant sciences and 6+ years of experience with GMP Utilities
- 5 years’ experience with sterile injectables, combo-devices, or biologics.
- Start-up experience preferred.
- Advanced degrees or certification relevant to the role is a plus.
- Ability to think strategically and tactically (detail-oriented).
- Strong collaborative and influencing skills, and ability to work well in a cross-functional, matrixed environment.
- Demonstrated ability to work in a fast-paced team environment, meet deadlines, and prioritize work.
- Proven track record of being self-motivated and capable of working with cross-functional teams while remaining positive towards project challenges.

Virginia

GRAIL Inc

Staff Software Engineer, Build Systems (Bazel) - #4770

Our mission is to detect cancer early, when it can be cured. We are working to change the trajectory of cancer mortality and bring stakeholders together to adopt innovative, safe, and effective technologies that can transform cancer care.

We are a healthcare company, pioneering new technologies to advance early cancer detection. We have built a multi-disciplinary organization of scientists, engineers, and physicians and we are using the power of next-generation sequencing (NGS), population-scale clinical studies, and state-of-the-art computer science and data science to overcome one of medicine’s greatest challenges.

GRAIL is headquartered in the Bay Area of California, with locations in Washington, D.C., North Carolina, and the United Kingdom. It is supported by leading global investors and pharmaceutical, technology, and healthcare companies.

For more information, please visit [grail.com](<http://grail.com/>)

GRAIL is seeking a Build Engineer to join our DevOps / Platform Engineering organization. Our team builds and operates the infrastructure, tooling, and developer platforms that engineering and research teams rely on to move quickly and safely, from local development environments through builds, tests, CI/CD, and release.

In this role, you will focus on developer experience: reducing friction in day-to-day engineering workflows and making complex, multi-language systems easier to build, test, and maintain. You will own and improve build-system workflows in our Bazel-based monorepo, raise CI reliability and performance, and build internal tooling and self-service automation used across engineering and research. This is a high-leverage role with broad visibility, your work directly accelerates teams working on early cancer detection.

This role is based in Sunnyvale, California. This role offers a flexible work arrangement, with the ability to work from GRAIL's office or from home. Our current flexible work arrangement policy requires that a minimum of 60%, or 24 hours, of your total work week be on-site. Your specific schedule, determined in collaboration with your manager, will align with team and business needs and could exceed the 60% requirement for the site. At our Sunnyvale campus, Tuesdays and Thursdays are the key days where we encourage on-site presence to engage in events and on-site activities.

**Responsibilities**

- Own and improve build-system workflows in our Bazel-based monorepo, including build rules, test execution, dependency management, caching, and build diagnostics.
- Improve CI performance, reliability, and observability, including failure diagnostics, flaky-test handling, and pipeline maintainability.
- Partner with engineering and research teams to identify and remove friction in local development, builds, tests, CI, release workflows, and tooling.
- Build and maintain internal tools, automation, and self-service workflows that reduce repeated manual effort for engineers.
- Diagnose complex build and CI failures across Go, Python, TypeScript, and Java codebases.
- Collaborate with DevOps and platform engineers on AWS and Kubernetes infrastructure where it intersects with build, test, and delivery workflows.
- Establish practical standards, documentation, and reusable patterns for build systems, CI pipelines, and developer tooling.
- Take accountability for ambiguous developer-productivity problems and drive them through to measurable improvements.
- Use modern AI coding agents responsibly to explore unfamiliar codebases, investigate difficult failures, prototype solutions, and accelerate tooling work.

*These responsibilities summarize the role's primary responsibilities and are not an exhaustive list. They may change at the company's discretion.*

**Required Qualifications**

- 6+ years of experience working on build systems, CI/CD, or developer productivity / platform tooling.
- 2+ years of hands-on experience with a large-scale build system (for example Bazel, Buck, Pants, Gradle, or CMake).
- 2+ years of experience building and maintaining CI/CD pipelines in GitLab CI, GitHub Actions, Jenkins, or a comparable system.
- 3+ years of professional coding experience in one or more of Go, Python, TypeScript, or Java.
- 1+ years of hands-on experience with AWS and containerized workloads on Kubernetes.
- BS in Computer Science or a related technical field, or equivalent experience.

**Preferred Qualifications**

- Production Bazel experience, especially in a large, multi-language monorepo.
- Experience with Bazel rules and toolchains, remote caching, remote execution, test sharding, or build performance optimization.
- Experience with dependency management, hermetic and reproducible builds, and test infrastructure at scale.
- Experience improving developer experience in a mixed-language engineering environment (Go, Python, TypeScript, Java).
- Experience building internal CLIs, automation, release tooling, or self-service developer platforms.
- Experience defining and using developer-productivity metrics to prioritize work and demonstrate impact.
- Experience diagnosing and reducing CI flakiness, build nondeterminism, and long-tail pipeline failures.
- Experience supporting scientific, research, or data-intensive teams, including Python packaging and container image workflows.
- Strong debugging skills across complex, multi-team build, test, and pipeline failures.
- Clear communication and collaboration skills, with a track record of working directly with developers, researchers, and platform engineers.
- Comfortable using modern AI coding agents as part of day-to-day engineering work while applying sound engineering judgment.
- Experience mentoring engineers or driving adoption of tooling and standards across teams.

The expected, full-time, annual base pay scale for this position is $169k-$223k.

At GRAIL, we believe in recognizing and rewarding the contributions our employees make to our mission and success. In addition to base pay, this role may be eligible for additional compensation, including an annual bonus and/or other incentives, in accordance with applicable plans and the company's discretion. The posted range reflects our good-faith estimate of the base pay we expect to offer for this position at the time of hire. Actual compensation will be determined based on factors such as the candidate’s experience, skills, qualifications, and other relevant considerations.

At GRAIL, we invest in the health, well-being, and future of our employees and their families. Employees in this role are eligible for a comprehensive and competitive benefits package designed to support what matters most, including flexible time off or vacation, a 401(k) retirement plan with employer match, medical, dental, and vision coverage, and thoughtfully selected well-being programs. Benefits are offered in accordance with applicable plans and policies.

GRAIL is an equal employment opportunity employer, and we are committed to building a workplace where every individual can thrive, contribute, and grow. All qualified applicants will receive consideration for employment without regard to race, color, religion, national origin, sex, gender, gender identity, sexual orientation, age, disability, status as a protected veteran, or any other class or characteristic protected by applicable federal, state, and local laws. Additionally, GRAIL will consider for employment qualified applicants with arrest and conviction records in a manner consistent with applicable law and provide reasonable accommodations to qualified individuals with disabilities. Please contact us at \[email protected\] if you require an accommodation to apply for an open position.

GRAIL maintains a drug-free workplace. We welcome job-seekers from all backgrounds to join us!

Pursuant to the San Francisco Fair Chance Ordinance, we will consider for employment qualified applicants with arrest and conviction records.

Senior Engineer: Mathematical Modeling and Simulation

**Join Amgens Mission of Serving Patients**

At Amgen, if you feel like youre part of something bigger, its because you are. Our shared missionto serve patients living with serious illnessesdrives all that we do.

Since 1980, weve helped pioneer the world of biotech in our fight against the worlds toughest diseases. With our focus on four therapeutic areas Oncology, Inflammation, General Medicine, and Rare Disease we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, youll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, youll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

**Senior Engineer Mathematical Modeling and Simulation**

**What you will do**

Lets do this. Lets change the world. Amgen's Combination Product Operations Digital and Data Strategies group is a process development team that develops and deploys innovative advanced simulation technologies towards improved process understanding, robustness and monitoring, and prediction and optimization of the manufacturing of combination products.

In this vital role you will support the team by incorporating physics and empirical techniques to develop rigorous finite element models (FEM) and numerical models of drug delivery devices (in-silico modeling assets) and improving the way Amgen manages and uses in-silico models to enhance decision making within the organization.

The candidate will apply engineering principles to develop efficient and trustworthy models addressing a wide variety of challenging problems associated with advanced material modelling, device design, characterization, verification, validation, manufacturing and tolerance analysis.

The ideal candidate enjoys tackling challenges and excels at developing functional in-silico models of combination products that enable insights for root cause investigation and design robustness supporting lifecycle management activities and complaint reduction.

**Responsibilities**:

- Implementing explicit and implicit FEM structural models. Ensuring that the approach and simplifications used to build these models is efficiently representing the physical system.
- Applying engineering principles like kinematic, structural, and tolerance analysis combined with material characterization and testing to create in-silico models able to capture the behavior of the device during use, assembly and transport.
- Continuous improvement of in-silico models, managing the lifecycle of the model and improving methods and workstreams to guarantee efficiency and trustworthiness of the models.
- Demonstrating critical and analytical thinking skills to explore new opportunities in in-silico and data-driven computational models. Modeling real-world scenarios with the adequate level of detail and help inform the decision making in a reduced time frame.
- Simulate complaints and real-world issues within lifecycle of combination products. Being able to apply an analytical approach to create models that accurately represent the real world scenarios and helps identify the root cause analysis of any complaint.
- Providing positive leadership and delivering work in a fast-paced, multi-project, cross-functional environment. Delivering predictions and insight on time to solve challenging production and customer problems..
- Model ownership, responsible for developing and managing backlog of in-silico product projects. Being able to concisely communicate on the modelling scope, limitations and assumptions to stakeholders with a technical and not technical background. Mentor also other simulation experts in the best use of simulation technologies.

It is expected that the Senior Engineer Modeling and Simulation will not only lead and collaborate heavily with internal team members, but also document and communicate the underlying technical basis of the models for the benefit of and use by the broader engineering and scientific community responsible for design and manufacture of drug delivery devices.

**What we expect of you**

We are all different, yet we all use our unique contributions to serve patients. The Engineer professional we seek is an individual with these qualifications.

**Basic Qualifications:**

Doctorate degree

OR

Masters degree and 2 years of**Engineering**experience

OR

Bachelors degree and 4 years of**Engineering**experience

OR

Associates degree and 8 years of**Engineering**experience

Or

High school diploma / GED and 10 years of**Engineering**experience

**Preferred Qualifications:**

- Finite element model experience with a commercial platform like SIMULIA, ANSYS, ALTAIR or COMSOL.
- Experience in explicit FEM modelling and non-linear structural models; contact modelling, large deformations, plasticity, and hyperelasticity.
- Knowledge of statistic and robustness analysis principles, being able to create models capturing the inherent variability in the process and device dimensions.
- Skilled in programming in Python, and/or MATLAB for engineering purposes. Scripting using commercial software codes like abaqus user subroutines, Tcl/Tk to automate model creation and post/processing.
- Experience with combination products and device regulatory requirements, medical device development and design controls, and knowledge of process controls.
- Excellent communication, presentation, and technical documentation skills are highly desired.
- Intellectual curiosity with ability to learn new concepts/frameworks, algorithms, and technology rapidly as needs arise.
- Ability to manage multiple competing priorities simultaneously and work in highly collaborative, cross-functional environments.

**What you can expect of us**

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, well support your journey every step of the way.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:

- A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
- A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
- Stock-based long-term incentives
- Award-winning time-off plans
- Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies.

**Apply now and make a lasting impact with the Amgen team.**

**careers.amgen.com**

In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information.

Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

**Sponsorship**

Sponsorship for this role is not guaranteed.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

Sr Engineer

**Join Amgens Mission of Serving Patients**

At Amgen, if you feel like youre part of something bigger, its because you are. Our shared missionto serve patients living with serious illnessesdrives all that we do.

Since 1980, weve helped pioneer the world of biotech in our fight against the worlds toughest diseases. With our focus on four therapeutic areas Oncology, Inflammation, General Medicine, and Rare Disease we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, youll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, youll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

**Sr Engineer**

**What you will do**

Lets do this. Lets change the world. In this vital role you will join the Packaging Engineering group within Combination Product Operations supporting Amgens global packaging network. This Senior Engineer role is designed for engineers from a range of technical disciplines, including packaging, mechanical, material science, chemical, manufacturing, process, systems, industrial, and biomedical engineering. You will be accountable for reliable delivery of technical work within defined projects, systems, or components while applying engineering fundamentals, scientific thinking, and regulated operations experience to develop, implement, maintain, and improve Packaging platforms, packaging configurations, processes, and related lifecycle activities. You will contribute to execution and coordination across teams, make sound technical decisions within established direction and standards, identify risks within your scope, and help ensure work progresses effectively within established plans.

- Own technical deliverables for assigned projects, components, systems, or platform areas, ensuring work is completed with consistent quality, reliability, and compliance.
- Develop, implement, maintain, and improve Packaging platforms that support product supply, technology transfers, and lifecycle management.
- Evaluate, recommend, qualify, and sustain packaging components, materials, processes, and platform elements for pharmaceutical products.
- Apply sound engineering judgment and scientific principles within established standards to solve moderately complex technical problems involving materials, product presentations, equipment, automated processes, documentation, and manufacturing interfaces.
- Identify technical risks, gaps, and issues within scope; anticipate downstream impacts; drive timely resolution; and escalate appropriately with context and potential solutions.
- Lead or support technical assessments, test protocols, qualification activities, engineering reports, specifications, procedures, and change controls.
- Support technology transfers from clinical to commercial and site to site for packaging configurations, equipment, and processes.
- Partner with Product Development, Operations, Manufacturing, Quality, Regulatory, Supply Chain, and other functions to deliver robust, compliant, and scalable packaging solutions.
- Establish priorities, manage project plans and dashboards, communicate progress and issues clearly, and drive work to completion within expected timelines.
- Identify and implement incremental improvements to processes, designs, tools, documentation, or ways of working within defined scope.
- Share knowledge, support team problem-solving, and provide guidance to junior engineers when needed.
- Ensure cGMP, regulatory, and change control expectations are met, and support regulatory inspections or related activities as needed.

**What we expect of you**

We are all different, yet we all use our unique contributions to serve patients. The professional we seek is a leader with these qualifications.

**Basic Qualifications:**

Doctorate degree

OR

Masters degree and 2 years of **Engineering** experience

OR

Bachelors degree and 4 years of **Engineering** experience

OR

Associates degree and 8 years of**Engineering** experience

OR

High school diploma / GED and 10 years of **Engineering** experience

**Preferred Qualifications:**

- Experience in packaging engineering, manufacturing engineering, process engineering, product development, device or combination product development, clinical supply, or regulated technical operations.
- Experience developing, implementing, maintaining, or improving clinical or commercial packaging configurations, equipment, processes, or lifecycle management programs.
- Experience supporting technology transfers, new product introductions, site start-ups, platform standardization, automated equipment implementation, or process improvements.
- Knowledge of cGMP expectations, change control, qualification, validation, technical writing, and regulated manufacturing environments.
- Demonstrated ability to own technical deliverables, deliver consistent high-quality work, identify and address risks within scope, and escalate issues appropriately with recommended solutions.
- Ability to collaborate effectively with cross-functional partners, communicate technical progress and issues clearly, and contribute constructively to team discussions and alignment.
- Demonstrated ability to identify incremental improvement opportunities in processes, designs, tools, documentation, or ways of working.
- Strong project management, communication, collaboration, technical writing, and technical problem-solving skills.

**What you can expect from us**

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, well support your journey every step of the way.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:

- A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
- A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
- Stock-based long-term incentives
- Award-winning time-off plans
- Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies.

**Apply now and make a lasting impact with the Amgen team.**

**careers.amgen.com**

In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information.

**Application deadline**

Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

**Sponsorship**

Sponsorship for this role is not guaranteed.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation. Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

Senior Manager Packaging Engineering

**Join Amgens Mission of Serving Patients**

At Amgen, if you feel like youre part of something bigger, its because you are. Our shared missionto serve patients living with serious illnessesdrives all that we do.

Since 1980, weve helped pioneer the world of biotech in our fight against the worlds toughest diseases. With our focus on four therapeutic areas Oncology, Inflammation, General Medicine, and Rare Disease we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, youll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, youll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

**What you will do**

Lets do this. Lets change the world! In this vital role you will report to the Director of Commercial Secondary Packaging and be based in Ohio, leading a team of engineers responsible for supporting commercial secondary packaging operations for final and WIP product presentations. This role is focused on ensuring reliable, compliant, and efficient packaging processes to meet ongoing commercial supply demands.

The Senior Manager will set priorities and direction for the packaging organization to support day-to-day manufacturing, drive operational excellence, and continuously improve packaging performance across commercial operations. You will collaborate closely with site functions including Manufacturing, Quality, Supply Chain, and Maintenance to ensure consistent delivery of high-quality product to patients.

**Specific responsibilities include but are not limited to:**

- Lead and develop a team of packaging engineers supporting commercial operations, ensuring timely resolution of production issues.
- Drive troubleshooting and root cause analysis for deviations, implementing effective CAPAs.
- Improve packaging line performance through enhanced equipment reliability, process robustness, and operational efficiency.
- Own packaging configurations, specifications, and maintenance of the qualified state for commercial products.
- Partner with Manufacturing, Quality, and **External Supply** to ensure compliance with regulatory requirements and inspection readiness.
- Lead continuous improvement initiatives to reduce downtime, waste, and process variability.
- Support change control activities, including packaging updates, material changes, and process improvements across internal and external sites.
- Provide regular updates to site leadership on performance, key issues, and improvement efforts.
- Collaborate with cross-functional, network, and **external partners** to align on standards and share best practices.
- Manage resources and priorities to meet production schedules and business needs.
- Provide technical oversight to external partners and suppliers supporting packaging operations.

**What we expect of you**

We are all different, yet we all use our unique contributions to serve patients. The packaging professional we seek will possess these qualifications.

**Basic Qualifications:**

Doctorate degree and 2 years of Engineering, Materials Science, or Industrial Design experience

OR

Masters degree and 6 years of Engineering, Materials Science, or Industrial Design experience

OR

Bachelors degree and 8 years of Engineering, Materials Science, or Industrial Design experience

OR

Associates degree and 10 years of Engineering, Materials Science, or Industrial Design experience

OR

High school diploma / GED and 12 years of Engineering, Materials Science, or Industrial Design experience

In addition to meeting at least one of the above requirements, you must have a minimum of 2 years experience directly managing people and/or leadership experience leading teams, projects, programs, or directing the allocation or resources. Your managerial experience may run concurrently with the required technical experience referenced above

**What you can expect of us**

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, well support your journey every step of the way.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:

- A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
- A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
- Stock-based long-term incentives
- Award-winning time-off plans
- Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies.

**Apply now and make a lasting impact with the Amgen team.**

**careers.amgen.com**

In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information.

**Sponsorship**

Sponsorship for this role is not guaranteed.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.